Efficacy and Safety of Surgical Decompression in Patients with Cervical Spondylotic Myelopathy
نویسندگان
چکیده
Michael G. Fehlings, MD, PhD, Jefferson R. Wilson, MD, Branko Kopjar, MD, PhD, Sangwook Tim Yoon, MD, PhD, Paul M. Arnold, MD, Eric M. Massicotte, MD, Alexander R. Vaccaro, MD, PhD, Darrel S. Brodke, MD, Christopher I. Shaffrey, MD, Justin S. Smith, MD, Eric J. Woodard, MD, Robert J. Banco, MD, Jens R. Chapman, MD, Michael E. Janssen, DO, Christopher M. Bono, MD, Rick C. Sasso, MD, Mark B. Dekutoski, MD, and Ziya L. Gokaslan, MD
منابع مشابه
CERVICAL SPONDYLOTIC MYELOPATHY: THE PATTERN OF NEUROLOGIC DEF ICITS AND IMPROVEMENT FOLLOWING ANTERIOR
We evaluated the specific pattern of pre- and postoperative neurological signs and symptoms of cervical spondylotic myelopathy (CSM) to determine [mdings which had a predictive value for surgical outcome. Consecutive patients with CSM caused by osteophytic ridge or intervertebral disc herniation who underwent anterior cervical decompression and fusion in Loghman Hakim Hospital from 1999-200...
متن کاملComparison of the safety and efficacy of anterior ‘skip’ corpectomy versus posterior decompression in the treatment of cervical spondylotic myelopathy
BACKGROUND The aim of this study was to compare the therapeutic effects of anterior 'skip' corpectomy with posterior decompression for treating four-level cervical spondylotic myelopathy. METHODS Operation time and blood loss during the operation for the anterior and posterior approach groups were recorded. Patients were examined with cervical lateral radiography before and after the operatio...
متن کاملHuman neuropathological and animal model evidence supporting a role for Fas-mediated apoptosis and inflammation in cervical spondylotic myelopathy.
Although cervical spondylotic myelopathy is a common cause of chronic spinal cord dysfunction in humans, little is known about the molecular mechanisms underlying the progressive neural degeneration characterized by this condition. Based on animal models of cervical spondylotic myelopathy and traumatic spinal cord injury, we hypothesized that Fas-mediated apoptosis and inflammation may play an ...
متن کاملPredicting Unilateral Postlaminectomy C5 Palsy by Measuring C5 Exit Foramen Area on Preoperative Computed Tomography
Background. Postoperative C5 motor palsy is known as a common complication not only after cervical laminectomy but also after anterior discectomy. There is no consensus to verify any of the proposed mechanisms of C5 palsy following posterior cervical decompression. The authors of this article have found that C5 palsy is more common among patients with smaller C5 root exit foramen area. The purp...
متن کاملVertebral Body Reconstruction using Expandable Titanium Cages after Anterior Decompression for Cervical Spondylotic Myelopathy: A Review
Objective: Cervical spondylotic myelopathy is a progressive debilitating disease that favorably responds to surgical decompression. The objective of this study was to review the use of expandable titanium cages for reconstruction of the spine after cervical corpectomy. Methods: We searched PubMed and Google Scholar databases up to March 2013 to identify English articles reporting the use of exp...
متن کاملAxonal plasticity underpins the functional recovery following surgical decompression in a rat model of cervical spondylotic myelopathy
Cervical spondylotic myelopathy (CSM) is the most common spinal cord disorder and a major cause of disability in adults. Improvements following surgical decompression are limited and patients often remain severely disabled. Post mortem studies indicate that CSM is associated with profound axonal loss. However, our understanding of the pathophysiology of CSM remains limited.To investigate the hy...
متن کامل